Search on: INHIBITOR WAP3, PROTEASE 
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Descriptor English:   Elafin 
Descriptor Spanish:   Elafina 
Descriptor Portuguese:   Elafina 
Synonyms English:   Peptidase Inhibitor 3, Skin-derived
Protease Inhibitor 3, Skin-derived
Protease Inhibitor WAP3
Skin-Derived Antileukoproteinase
Antileukoproteinase, Skin-Derived
Inhibitor WAP3, Protease
Peptidase Inhibitor 3, Skin derived
Protease Inhibitor 3, Skin derived
Skin Derived Antileukoproteinase  
Tree Number:   D12.644.822.437
D12.776.645.437
Definition English:   A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG. 
Pharmacological Action:   Protease Inhibitors
 
History Note English:   2007(2005) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52318 
Unique Identifier:   D053492 

Occurrence in VHL: 		 

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